This paper brings forth an overview of design and interaction within realms stretching from reality to virtuality. In recent years, architects have been exploring creative technologies and potentials using a variety of interfaces ranging from real and virtual to augmented reality (AR) and mixed reality (MR) media. The process of design and method of communication are becoming increasingly imperative for inter-disciplinary work. This highlights the need for a structured review of successful effective adoptions and settings of those realms and technologies. This paper critically reflects on lessons learned from architectural design research, which employ virtual, augmented, mixed and real environments, and address rising issues in these areas.